30YR OLD FEMALE WITH RODENTICIDE CONSUMPTION (? Yellow phosphorus)

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30 yr female came to casuality with c/o consumption of rat poison (RATOL PASTE ? YELLOW PHOSPHORUS -1 full tube approx 15g, 2 weeks ago)

DAY 2 - VOMITINGS 3- 5 EPISODES (food as contents) and diarrhea episodes for 24 hours.

DAY 3 - vomitings subsided but developed yellowish discoloration of eyes

DAY 6 - Developed PEDAL EDEMA and Shortness of breath (SOB of sudden onset , progressive) 

DAY 7 was admitted at local hospital outside

DAY 10 Constipation and decreased urine output  

DAY 12 was brought to our hospital with no urine output since one day , in irritable condition.

Past history:

No H/O  DM, HTN, CAD, Asthma , previous liver disease .


General Examination: 

 Patient was concious , coherent and cooperative and oriented to time place and person 

Patient was irritable 

Temp- 98.6 F



BP- 120/80 mmhg

PR- 78 bpm

RR- 18 cpm

SpO2- 97% at 8lit o2



No pallor

Icterus present



No cyanosis, clubbing, lymphadenopathy

Mild pedal edema is seen 




Systemic Examination:

CVS- S1 S2 +,no murmurs

CNS- Patient is irritable 

RS- BAE+, reduced breath sounds in b/l IAA , ISA

P/A- Distended, Petechial rashes +, tense 


Distended abdomen:




 Petechial rashes: 

Urine bag



Investigations: 

Hemogram 

Liver function tests

Radiological findings:

ECG:

X-ray - bedside 
Planned for PLEURAL and ASCITIC TAP

Provisional diagnosis: 

? YELLOW PHOSPHORUS POISONING with ACUTE LIVER FAILURE and ACUTE LUNG INJURY (PLEURAL EFFUSION) 



Treatmemt:

Ivf NS,RL,DNS @UO+30ml/hr

Inj.OPTINEURON 1 amp in 100ml NS IV OD

Inj.Vit K 10mg IV OD slow iv

Inj.PAN 40mg iv od

Inj.ZOFER 4mg IV BD

Syp.LACTULOSE 20ml PO H/S

Inj.NAC 6000mg in 500 NS over 4hrs , f/b 2000mg in 500ml NS over 8hrs,  f/b 400mg in 500ml NS over 16hrs

Inj.MONOCEF 1gm IV bd

Syp.LIV 52 10ml po bd

Ivf dns with 8U HAI IV stat over 3 hrs.

Inj. Dexmedetomidine 1amp + 49 ml NS @5ml/hr 

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